Based on the integrated requirements of load-bearing and electrical functions of aviation wall panel, an optimized design and an experimental verification are conducted to heterogeneous composite material wall panel suitable for intelligent skin. By adding a glass fiber layer in the outer side of the high modulus carbon fiber skin, a wall panel load-bearing electrical functional integration design is carried out in the order of carbon fiber glass fiber metal structural unit array glass fiber composite. The layer optimization of heterogeneous composite material structures is in consideration of the zoning of co bonding and the process requirements for layer continuity. An optimization method based on layer dropping sequence is developed, and the geometric shape, number of ribs, geometric parameters of ribs, and layer angle between ribs and skin of the reinforced wall panel are optimized. The benefits of the structure in terms of load-bearing capacity and stability are verified through compression stability tests, and the buckling mode and post buckling failure mechanism under compression load are clarified.