In order to improve the loading performance of UAV, a new type aerodynamic configuration of joined wing with twinfuselage is designed, and a basic and improved layout model is established. The aerodynamic characteristics of the two configurations are studied in detail by FLUENT. The simulation results show that the joinedwing with twinfuselage layout is good in aerodynamic performance, its lifttodrag ratio in cruise can reach more than 16. With the improvements such as blended wingbody, nose modification and connection procession at front and rear wings, its liftdrag performance greatly improves. When the angle of attack (AOA) is at 2°, the lift coefficient and lifttodrag ratio of improved configuration increase by 1.8% and 9.1% respectivly, the drag coefficient is reduced by 6.7%, and the stall performance is higher. Besides, compared with the basic configuration, the pressure distribution in nose and wingbody connection of improved configuration is effectively reduced with AOA of 2°, the significantly separation doesn’t occur at rear wing of improved configuration at the AOA of 12°. The preliminary flight test shows that both configurations possess excellent flight performance, and there is hope of an application in military and civilian transportation, rescue, reconnaissance and other fields.