This paper mainly discusses how to reconcile the test results with the service data to solve fatigue safe-life of aircraft structure. Aimed at the fatigue life obedient to the Log-normal distribution or Weibull distribution, the service flying hours and test results can be reconciled directly to analyze the reliability for the aircraft structure. Aimed at the fatigue life disobedient to the Log-normal distribution or Weibull distribution, the service hours can be transformed into the equivalent flying hours at the same test load spectrum according to the equal damage to realize the fusion of the test data and the service data. The parameters of fatigue safe-life distribution function can be estimated by using the method of maximum likelihood function in accordance with the fusion data. The fatigue safe-life for aircraft structure is analyzed by using the estimated parameters and the fusion data. The result shows that the sample capacity is increased obviously after the data fusion, and the life reserve of reliability is excavated adequately by adopting the method of the fusion data under the conditions of the same reliability and confidence level.