In order to improve the anti-TBM effectiveness of the surface to air missile weapon, the problem that the disposition of one piece of the surface to air missile weapon system is studied in the paper. Firstly, some major factors that influence the surface to air missile weapon system intercepting TBM are analyzed. Secondly, the rule of the maximum killed depth (KD) is put forward. Finally, by taking the reentry angle of TBM into account and making use of the ballistic trajectory character of approximately beeline, the two optimal models of anti-TBM defense disposition are established which are about "single to single" and "single to multi" fighting patterns. At last, an example simulation is given, which testifies that the models are effective, feasible available and can meet the demand of anti-TBM.