A simplified equivalent strain model is presented to predict the disk Low Cycle Fatigue (LCF) life aimed at unsymmetrical loads and the main life regions. Using this model, the LCF life of the first high-pressure compressor disk is predicted. A series of axial strain-controlled LCF tests of 1Cr11Ni2W2MoV bar specimens are conducted. Then an experimental disk is designed, and the LCF test of the rotor is carried out on the spin test rig. The average LCF test life of three disks, 4 280 test cycles, is obtained. Compared with the test life, the prediction error of equivalent strain model is 41.8%, and that of Manson-Coffin model is 99.2% .The result indicates that the disk LCF life prediction method based on the equivalent strain is effective, and is higher than the Manson-Coffin method in accuracy of life prediction.