In order to accurately predict target intention prediction and help decision-making timely and reasonably, the D-S evidence theory is adopted in target intention prediction. First, the situation factors are extracted, and then the influence of each factor is analyzed, based on which, the mathematic modeling is created. With the D-S composition law, the influences of all factors are integrated, the probability evaluates of the likely propositions are calculated and the corresponding decision is made. Numerical examples of simulation show that the uncertain probability decreases greatly after fusion, the result of target intention prediction is reasonable, and the method can be extended to multi-formation.