The influence of multi-band interference on ultra-wideband (UWB) communication is analyzed in this paper. The closed form of the JR expression is derived based on the Gaussian pulse waveform. The direct sequence spread spectrum communication (DS - SS) and frequency hoping spread spectrum communication (FH - SS) are respectively compared with UWB communication in performance and analyzed in the presence of multi-band interference. According to common variable of the above three communication models, the JR performance curves can be simulated respectively. A comparison based on JR parameter between the multi-band interference suppression capabilities of above three communication models is carried out, which shows that in most cases, the multi-band interference suppression of UWB is superior to that of DS - SS and FH - SS.