Lightweight and multifunctional design become the urgent needs of our army weapons and equipment. Taking metallic foam and lattice structures as representative, these materials are characterized by ultralight and high energy absorption efficiency. However, core web buckling of metal lattice core and low strength of the metallic foam critically limit their engineering applications. In this paper, multilayer metallic sandwich structures with empty and aluminum foamfilled corrugated cores of three different configurations are obtained by filling aluminum foam into the space of the corrugated cores, and their load carrying and energy absorptioncapabilities are experimentally studied under outofplane compressive load. The results show that the peak compressive strength and specific energy absorption of the foamfilled panels canbe 93 and 218 times as high as those of the empty panels, and even increase by 19％ and 20％compared with aluminum foam respectively. The coupling enhancement mechanism indicates that the filling of the aluminum foam transforms the buckling mode of the corrugated core memberinto a highorder one, resulting in a substantial increase in strength and energy absorption efficiency. The excellent performance in load carrying and energy absorption of the novelsandwich structure with hybrid core make it competitive in integrative design of light weightstructures.