In view of the hypersonic vehicle quasi-equilibrium glide reentry problem, the various constraints in the process of reentry are analyzed. Process constraints are converted to a bank angle constraint at different stages, and a bank angle file is designed based on the above described. With the performance indicators of maximum cross-range and minimum aerodynamic heating, GA combined with pattern search method is used to find the optimal solution for the reentry trajectory while the terminal constraints are dealt by using the penalty function. The simulation shows that the reentry trajectory satisfactory to the various constraints can be planned by using the designed bank angle file. The speed of the algorithm optimization is raised, and still more close to the online program. This method can be used for rapid trajectory optimization and research in the covered area.